"Joe and Gray Wolf Hate to inform you that suppositories don't work for administration of THC without being bound to hemisuccinate. That's why they don't get you high, because THC doesn't enter your bloodstream. I've been doing a lot of suppository research because I think theres a lot of misconceptions being spread. I've gotten every doctor and site I've talked to to take down articles in support after seeing this info. Primary Sources "Disposition and bioavailability of various formulations of tetrahydrocannabinol in the rhesus monkey" http://onlinelibrary.wiley.com/doi/10.1002/jps.2600740213/abstract "Rectal bioavailability of ?-9-tetrahydrocannabinol from the hemisuccinate ester in monkeys" http://onlinelibrary.wiley.com/doi/10.1002/jps.2600801008/full Overview http://www.greenbridgemed.com/latest-thoughts-on-rectal-administration/"